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Donald E. Ingber (born May 1, 1956, East Meadow, NY) is an American cell biologist and bioengineer, the Founding Director of the Wyss Institute for Biologically Inspired Engineering at Harvard University, the ''Judah Folkman Professor of Vascular Biology'' at Harvard Medical School and Boston Children's Hospital, and Professor of Bioengineering at the Harvard School of Engineering and Applied Sciences. He is also a member of both the American Institute for Medical and Biological Engineering and the Institute of Medicine of the U.S. National Academies. Ingber is a founder of the emerging fields of biologically inspired engineering. He has made pioneering contributions to numerous other disciplines including mechanobiology, cytoskeletal biology, extracellular matrix biology, integrin signaling, tumor angiogenesis, tissue engineering, nanobiotechnology, systems biology, and translational medicine. Ingber has authored almost 400 publications in scientific journals and books, and is an inventor on more than 90 patents spanning anti-cancer therapeutics, tissue engineering, medical devices, drug delivery systems, biomimetic materials, nanotherapeutics, and bioinformatics software. In addition to serving as director of the Wyss Institute at Harvard University, Ingber currently heads active laboratories in the Biomimetic Microsystems Platform at the Wyss Institute and in the Vascular Biology Program at Boston Children's Hospital, which are located in adjacent buildings in the Longwood Medical and Academic Area of Boston. In the Biomimetic Microsystems platform at the Wyss, microfabrication techniques from the computer industry are used to build functional circuits with living cells as components. The Ingber Laboratory at Children's Hospital addresses the fundamental problem of how cells decide whether to move, grow, contract, differentiate, or die during tissue development. The major focus is on angiogenesis—the growth of blood capillaries—a process that is critical for the growth of cancer and many other debilitating diseases. The group is also developing novel cancer reversal therapies. Ingber has been scientific founder of three companies: Neomorphics, Inc.,〔(【引用サイトリンク】url=http://www.bloomberg.com/research/stocks/private/snapshot.asp?privcapId=22354525 )〕 a tissue engineering startup which led to clinical products through subsequent acquisitions (Advanced Tissue Sciences Inc.); Molecular Geodesics, Inc., (later known as Tensegra, Inc.)〔(【引用サイトリンク】url=http://www.bloomberg.com/research/stocks/private/snapshot.asp?privcapId=31677 )〕 which 3D-printed medical devices; and most recently, Emulate, Inc.,〔(【引用サイトリンク】url=http://www.businesswire.com/news/home/20140728005140/en/Emulate-Launches-Commercialize-Automated-Human-Organs-on-Chips-Platform )〕 which formed in 2014 to commercialize human ‘organs-on-chips’ that accelerate drug development, detect toxicities and advance personalized medicine by replacing animal testing. ==Education and academic research== Ingber received a combined B.A./M.A. in molecular biophysics and biochemistry from Yale College and Yale Graduate School in 1977; a M.Phil. in cell biology from Yale Graduate School in 1981; and a combined M.D./Ph.D. from Yale University School of Medicine and Yale Graduate School in 1984. At Yale University, he carried out undergraduate research on DNA repair with (Paul Howard-Flanders ) and on cancer metastasis with Alan Sartorelli. Ingber worked on development of cancer therapeutics with Kenneth Harrap at the Royal Cancer Hospital/Royal Marsden Hospital in England with support from a Bates Traveling Fellowship. Ingber carried out his Ph.D. dissertation research under the direction of Dr. James Jamieson in the department of cell biology, and his advisory committee included George Palade, Elizabeth Hay and Joseph Madri. From 1984 to 1986 he completed his training as an Anna Fuller Postdoctoral Fellow〔(【引用サイトリンク】url=http://www.engineerdir.com/dictionary/catalog/3643/ )〕 under the mentorship of Dr. Judah Folkman in the Surgical Research Laboratory at Boston Children's Hospital and Harvard Medical School.〔(【引用サイトリンク】url=http://www.rsc.org/Publishing/Journals/lc/EBDetails/DonaldIngber.asp )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Donald E. Ingber」の詳細全文を読む スポンサード リンク
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